In this article, we will discuss about the molecular basis of sickle cell anemia. It is a disease in which shape of the red blood cells due to a mutation in which valine replace the glutamic acid. We will discuss the several genetic and epigenetic factors that cause the disease. It is hereditary blood genetic disorder, that is due to mutation in beta chain of hemoglobin.Continue Reading

In this article, we will discuss about the models for the arrangement of DNA in chromosomes. This article explores the various models that elucidate the intricate arrangement of DNA within chromosomes. Throughout this piece, we will delve into the fascinating mechanisms and structures that facilitate the highly condensed nature of genetic material in chromosomes.Continue Reading

In this article, we will discuss in depth the molecular basis of cancer, which refers to the abnormal division and growth of cells in the body. Cancer is a complex disease that involves a multitude of genetic and environmental factors. Cancer can arise from various types of cells in the body, such as epithelial cells, connective tissue cells, blood cells, and others.Continue Reading

In this article, we will discuss about the translation of mRNA (synthesis of proteins from messenger RNA that act as template).It involves three different steps: initiation, elongation and termination. The initiator transfer RNA (tRNA) is necessary for the initiation of the translation. Several elongation factors in the elongation of the template.Continue Reading

In this article, we will discuss about the molecular basis of diabetes, that is caused by mutations in beta cells of pancreas. Diabetes is of two types: type I that is due to deficiency of insulin. Type II that is genetically inherited. We will discuss about the genetic factors and pathways to the causes of disease. Several environmental factors also effect the beta cells to cause the disease.Continue Reading

In this article, we will discuss about the transcription of DNA (synthesis of messenger RNA from DNA). The process of transcription is regulated by DNA-dependent RNA polymerase. One of the two strands of DNA acts as the coding strand and is identical to the single-stranded RNA. The other strand acts as the non-coding strand, complementary to RNA, and acts as a template for the synthesis of mRNA.Continue Reading